Rubella Virus

Rubella, most commonly known as German or 3-day measles, is caused by an RNA virus that belongs to the family Togaviridae. The infection is highly contagious and is spread through direct or droplet contact from nasopharyngeal secretions. The infection commonly affects children aged between 5-14 years as well as young adults. Rubella infection is largely benign with symptoms ranging from subclinical to a disease characterized by an erythematous rash, low-grade fever, headache, lymphadenopathy, arthralgia, and conjunctivitis.
Immunizations and natural infection both confer lifelong immunity and reinfection is extremely rare. Congenital Rubella infection, unlike acquired infection, may cause disastrous clinical effects to the unborn child. A fetus may be stillborn or have such abnormalities as bone and cardiovascular defects, mental retardation, encephalitis, hepatomegaly, splenomegaly, thrombocytopenic purpura, cataracts and microcephaly. Because of severity of the complication from infection, detection of active infection in pregnant women is paramount. Therefore, it is important that the level of immunity be determined in women of reproductive age, pregnant women, neonates who were exposed in utero, and others who may have been in close contact. As clinical recognition of Rubella infection upon physical examination is highly unreliable and subclinical cases are frequent, serological testing is vital to determine immune status and detect infection.

Sample Volume : 10 µl
Controls/ Calibrators : 5 Calibrators ( IgG ) 3 controls ( IgM )
Incubation : 45’+ 45’+15 min
Substrate : TMB